About this article series
Welcome to “Body Systems Demystified,” our article series where we unravel the fascinating mechanisms that drive the human body. My approach to supplement formulation begins with a deep appraisal of how the human body and all living systems (e.g. plants, animals, microorganisms) operate. Exploring the intricate interplay of body mechanisms and nutrients allows me to design supplements that address these mechanisms and deliver on their promise. Join me on this enlightening journey as we uncover the secrets behind human body mechanisms and gain valuable insights into the dynamic relationship between your body and optimal health.
Today’s Post: How Probiotics Fight Harmful Germs
The human gut is home to trillions of bacteria, both beneficial and harmful. Maintaining a delicate balance between these microorganisms is vital for optimal digestive health.
Probiotics, often referred to as “friendly bacteria,” play a crucial role in this delicate microbial ecosystem.
In this article, we explore how probiotics combat germs in the gut, fortify the body’s defense mechanisms, and promote overall well-being.
We will take a look at the fantastic picture below (source: ) which illustrates how probiotics help keep harmful microorganisms (also known as enteric pathogens) at bay in our intestines, a site where microorganisms can affect the body.
Before we begin, let’s keep in mind that probiotics are live microorganisms that provide health benefits when consumed in adequate amounts.
Probiotics can be found in various natural sources, primarily originating from two main categories: fermented foods like yogurt and sauerkraut, as well as supplements that contain specifiic strains isolated from the human body or the environment.
Here’s how probiotics work, using the illustration above.
A. By reinforcing the gut barrier
Probiotics can exert direct effects on the cells that line the intestines. These cells are called intestinal epithelial cells (IECs) and they make up a protective layer called the intestinal epithelium.
Probiotics can increase the secretion of mucin glycoproteins by goblet cells that assemble into a thick mucus layer.
Probiotics can augment the secretion of antimicrobial proteins (defensins) by IECs that help to eliminate pathogens that penetrate the mucus layer.
Probiotics can enhance the stability of intercellular junctional complexes (tight junctions (TJ)), which decreases the intercellular permeability of IECs to pathogens and other antigens.
B. By Producing Antibacterial Substances
Probiotics are known to produce antibacterial substances that directly inhibit the growth of harmful germs.
These substances include organic acids (such as lactic acid), bacteriocins, and hydrogen peroxide.
By secreting these antimicrobial compounds, probiotics create an inhospitable environment for pathogens, effectively suppressing their proliferation within the gut.
C. By competing against harmful microorganisms
Probiotics can compete with harmful microorganisms for adhesion sites in the mucus layer or IECs, thereby preventing harmful colonisation and enhancing barrier function.
Probiotics effectively compete with harmful germs for essential nutrients and resources within the gut environment. By utilizing available resources, probiotics limit the availability of nutrients required by pathogenic bacteria for their survival and growth. This competition can further restrict the colonization and proliferation of germs, maintaining a balanced and healthy gut microbiota.
By introducing beneficial strains, such as Lactobacillus and Bifidobacterium species, probiotics help create an environment unfavorable for the growth and colonization of harmful pathogens. This competitive exclusion mechanism prevents the overgrowth of detrimental bacteria, effectively combating germs within the gut.
Conclusion
Probiotics are a valuable ally in the fight against germs in the gut. Through multiple mechanisms, including restoring microbial balance, reinforcing the gut barrier, producing antibacterial substances, modulating the immune response, competing for resources, and stimulating mucus production, probiotics actively combat harmful pathogens. By promoting a healthy gut microbiota, probiotics play a vital role in maintaining digestive health and overall well-being. Incorporating probiotic-rich foods or supplements into your daily routine can provide the support your gut needs to fend off germs and maintain optimal health.
To view my Professional Profile on LinkedIn: please click here
To see my latest product creations: www.bioteenhealth.com
To view my Scientific Publications on PubMed: please click here
To get in touch, please write to: info@supplementscientist.com
Follow supplementscientist.com on Facebook: please click here
Disclaimers
Medical: The information presented on this website is intended for adults 18 or over. Its aim is purely educational and does not constitute medical advice. Please consult a medical or health professional before you begin any program related to exercise, nutrition, or supplementation especially if you have a medical condition. If you consume any product mentioned on our site, you do so on your own free will, and you knowingly and voluntarily accept the risks.
Other: The views expressed in this blog article are solely mine and do not represent the opinions or positions of any company or institution with which I am associated. Any information or opinions provided are based on my personal experiences, research, and understanding. I strive to ensure accuracy and reliability of the information provided.
© 2023. Supplementscientist.com
Leave a Reply